– Dose: – maximum dose for RA patients is 750 mg to 1 g per day; – low doses (125-250 mg) of the drug are used initially with slow-dose titration to reduce the potential for side effects. – D-penicillamine exhibits similar toxicity profile to IM gold, which includes mucocutaneous reactions, proteinuria, nephrotic syndrome, leukopenia, thrombocytopenia, … Read more
– See: Penicillin Family – DOC for Group A strep, pneumococcus, N. gonorrhea, syphilis; – good for most Gm positive, Streptococcus, Meningitis, Clostridium, Cornybacterium, coliforms, – prophylaxis for bacterial endocarditis; – Adult: 250-500 mg (400-800 K units) PO qid; – IV 1.2-24 million units per day; – Strep Pneumonia: 1-2 million units IV q4-6hr; … Read more
for moderate to severe pain; preop sedation; Synthetic partial opiate agonist/antagonist; Dosage:30mg IM or IV; 50-100mg PO q3-4hr prn; Note that 30-60mg IM equianalgesic to 10mg morphine IM; therefore, use with caution in patients receiving opiate drugs; associated with considerable dysphoria; KEY SEDATION PAIN OPIOID
(See Pen Family) – for Gm positive infections, Streptococcus, N.gonorrhea and Meningitis, Syphylis, Clostridium, Cornybacterium and prophylaxis for endocarditis; – Adult: 250-500mg PO q6hr; Well tolerated oral penicillin; – Also available 200,000 Units (125mg/5ml) 400,000 Units (250mg/5ml) for PO – Solution/suspension– administration; – Note prophylaxis of Bacterial endocarditis: 2.0gm PO 1hr before procedure and 1.0gm PO 6hrs … Read more
– every patient should be maintained on at least 5 cm H2O of PEEP; – objective of optimal PEEP is to reduce the intrapulmonary Shunt; – since cardiac output may also be decreased, fluid administration or vasoactive drugs may also be required to restore Cardiac Output; – if pulmonary wedge pressure is grossly elevated, … Read more
– Discussion: – occurs when pressure in a muscle compartment is > pressure in the capillaries, which leads to progressive muscle ischemia and edema and left untreated can result in infarction of the compartment contents; – ischemia and necrosis of the muscles occur even though the arterial pressure is still high enough to produce … Read more
– Discussion: – parathyroid hormone is 84 aa petide made & secreted from chief cells in 4 parathyroid glands; – parathyroid hormone (PTH) has been approved as an anabolic treatment for osteoporosis; – all actions of PTH are either directly or indirectly involved w/ maintaining serum ionic Ca concetration (see Ca hemostatsis); … Read more
* Pos: I, II, V4, V5, V6, AVF; Neg: AVR * Best Seen: II and V1; * Duration: PR: 0.12 – 0.20 msec; – < 0.12 msec: consider: – > 0.20 msec: consider: – Normal varient (large person); – Problem AV node: ? AV block, drug effect; – Intra Atrial Cond. defect: Hyper K, Large … Read more
– Discussion: – a chronic progressive disease osteoblasts and osteoclasts which results in abnormal bone remodeling; – etiology, staging, and pathogenesis – prevalence: – uncommon in pts under age of 55 yrs but relatively common in later life, occurring in 3-4% of persons over 55 yrs & occurs in 10% in pts over age 80; – reference: – … Read more
for anxiety with depression or ETOH withdrawl; Adult:10-15mg PO tid/qid; with severe anxiety or ETOH withdrawl try up to 30mg tid/qid; this is a metabolite of diazepam, must reduce w/ elderly; Contraindicated with pyschoses; Avoid concomitant use of ETOH, or other CNS depressant drugs; Note slow onset of action, t/2= 5-21hr; No active metabolites; Also … Read more