Ortho Oracle - orthopaedic operative atlas

Prochlorperazine/Compazine

– for N/V/Agitation/Antiemetic/Antipyschotic; – Adult: Antiemetic: 5-10 mg PO/IM/IV tid/qid, or 5-10mg deep IM q4-6hr; – Up to 40mg PO q6hr max; 25 mg PR q6-8 hr; – Antipyschotic: 10-20 mg IM acutely or 5-10 mg PO tid/qid for maintainance; – treat extrapyridimal effects with diphenhydramine 25mg in the bag, q6hr; – Contraindications include: comatose … Read more

PRAZEPAM/CENTRAX

for anxiety disorders;  Benzodiazepine related to chlordiazepoxide; Adult: 5-10mg PO 3 or 4 times qd; 20-50mg PO as single bed time dose to minimize daytime drowsiness;  CNS depressant activity may make some activities requiring concentration dangerous for patients (driving); Note that this drug designed for slow conversion to active product, peak: 4-12hr after dose;  Note … Read more

Plicamycin (Mithramycin)

– Discussion:     – inhibitor of RNA synthesis in osteoclasts;     – an effective treatment for hypercalcemia;     – given intravenously in a dose of 25 microg per kilogram over a period of four to six hours;     – dose can be repeated several times at intervals of 24 to 48 … Read more

Piperacillin / Pipracil

– See:        – Penicillin Family        – AntiPseudomonal Agents – Discussion:     – piperazine penicillin derivative with increased activity against many gm negative bacteria – P.aeruginosa, Enterobacteriacae – S.faecalis; Anaerobes (B.fragilis);     – for serious infect.: 200-300 mg/kg/24hr IV in 4-6 divided doses;     – for complicated … Read more

PHENYLEPHRINE/NEO SYNEPHRINE

– Discussion:  – for treatment of vascular failure in shock, hypersensitivity, or drug induced hypotension; – used to overcome paroxysmal SVT;  – blood pressure maintenance during spinal anesthesia;  – alpha agonist vasoconstrictor:  – Dosage:  – mild hypoTN: 2-5mg IM or SQ elevatesBP for 2 hrs; – 0.1-0.5 mg IV given as slow IV injection;  – … Read more

Phenytoin/Dilantin

– For grand mal and partial seizures; – Adult active siez:18-20mg/kg IV (50mg/min maximum infusion rate); – Oral loading: 15-20mg/kg in doses of 400mg or less at 4 hr intervals; – Maintainance doses: 300-400 mg/24 hr IV/PO divided q12-24 hr, based on plasma values and clinical response; – …or try: Loading dose 750 mg to 1 … Read more

Phenylbutazone/Butazolidin, Azolid

– Symptomatic treatment of acute gouty arthritis; rheumatoid spondylitis; – musculoskeletal disorders (peritendinitis, bursitis); acute perivascular inflamation; – NSAIA; dosage: 300-600 mg/day in 3-4 divided doses; – should reduce maintenance dose to minimum effective dose (maximum 400mg/day) – Note: erythematous maculopapular rash; – Note: use w/ caution in pts over 40 yrs; ocular and otic … Read more

Peptic ulcer disease: Gastritis: PUD

 – H2 blocker:    – Cimetidine        – Zantac            – Pepcid        – Nizatidine  – Other:    – Antacids    – Omerprazole    – Nexium    – Carafate    – Protonix    – Aciphex (rabeprazole sodium):           – proton pump inhibitor approved for … Read more