Ortho Oracle - orthopaedic operative atlas

Pathogenesis of RA

– Discussion:     – combination of genetic and environmental factors in its etiology;     – an important early event may result from the interaction of antigen presenting macrophages w/ T cells (helper/inducer);     – HLA-D allele DR4 is associated w/ RA patients;     – although clinical laboratories measure IgM rheumatoid factor, … Read more

Pathogenisis

– Discussion:     – AC arthritis or AC joint osteophytes can result in impingement and mechanical irritation to the rotator cuff tendons;     – similar phenomenon can occur after displaced AC separations;     – greater tuburosity fractures can cause impingement on the rotator cuff if the fragment rotates superiorly;     – humeral neck … Read more

Partial Patellectomy

– Discussion:     – not all patellar fractures are amenable to ORIF;     – in most cases of patellar frx, one large frag of patella can be preserved;            – most often the distal pole is comminuted, whereas superior pole is intact,however, as a principle, the larger                    fragment … Read more

Evaluation of the Painful Total Hip Replacement:

– See: THR Main Menu and Radiographic evaluation of THR – Discussion:      – normal gait adaptions:          – trendelenburg limp after THR is a clinical sign of gluteal insufficiency;                – static trendelenburg sign: drop of the pelvis on the contralateral side while the individual stands on the operative side;                – many patients will compensate for … Read more

Pagets Disease

– Discussion: – a chronic progressive disease osteoblasts and osteoclasts which results in abnormal bone remodeling; – etiology, staging, and pathogenesis – prevalence: – uncommon in pts under age of 55 yrs but relatively common in later life, occurring in 3-4% of persons over 55 yrs & occurs in 10% in pts over age 80; – reference: – … Read more

Pagets Disease: Etiology and Pathogenesis

– Etiology: disease may be caused by a virus;     – paramyxovirus infection of osteoblasts may activate of the c-fos proto-oncogene, resulting in localized abnormal osteoclastic activity typical of Paget’s disease; – Pathophysiology:      – in Paget’s disease, primary defect is in the remodeling system of isolated areas of skeleton;      – … Read more

Osteomyelitis in the Child

– Pathogenesis:     – osteomyelitis occurs most frequently in the long bones of lower extremities, & to a lesser extent the upper extremities;     – hematogenous osteomyelitis     – pediatric bone circulation: tortuous course of nutrient vessels in bone causes bacteria to be trapped in the metaphysis;     – epiphyseal plate prevents infection from entering the … Read more