-See:
-
Hypoparathyroidism:
-
Actions of PTH:
- Discussion:
- lack of responsiveness to
PTH due to defect in adenyl cyclase;
- clinical picture may resemble of
hypoparathyroidism;
- due to inability of bone & kidney to respond to parathyroid hormone,
hypocalcemia and
hyperphosphatemia
occur in spite of elevated parathyroid levels;
- pts w/ this disorder have a characteristic clinical appearance that includes short stature,
round facies, & shortened 4th metacarpals;
- subQ
calcifications that may be present in pseudohypoparathyroidism not present in the idiopathic disorder;
