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Wheeless' Textbook of Orthopaedics

Infected Femoral IM nails



- Discussion:
    - three types of infection:
            - infection of the soft tissues;
            - infection of the fracture site
            - infection of the entire marrow cavity:(rare but serious and may require AKA);
      - infection usually develops with in 3 weeks of IM nailing;
      - outstanding symptom is continuous deep thrombing pain, which is worse at night and persisting beyond
            usual period of postop discomfort;
            - intermittent fever, redness, warmth, tenderness, and marked swelling of the thigh are common;

- Management: Infection following IM nailing:
    - once a deep infection is diagnosed - the question is whether to remove nail;
    - 4 to 6 months is required for frx healing;
    - pt must be protected from septicemia, by thorough debridment of sequestra, infected tissue, open wound care and ATB
    - acutely infected IM nails should be irrigated and debridded at the frx site as well as the IM canal;
    - consider making a hole in distal medial aspect of femur to allow thorough irrigation of the canal;
    - stable intramedullary nail:
          - there is no gross motion is present, then leave nail in place if - at debridment of infection;
          - nail is usually left in place as long as frx fixation is maintained;
                - note that this strategy is probably not appropriate for infected tibial IM nails;
          - nail is removed if subsequent x-rays show evidence of bone resorption and lossening of the nail;
    - unstable intramedullary nail:
          - consider whether to add interlocking screws;
          - consdier whether to add a larger diameter exchange nail;
          - it has been shown that rigid stabilization of frx site is imperative in infected nonunions;
          - larger nail may be necessary to compensate for the extra reaming;
          - after frx union, which can be expected despite the infection, nail can be removed;
          - nail is removed, canal overreamed to remove infected granulation tissue from the canal, canal
                  is irrigated thoroughly, & larger nail is inserted;
                  - note that this strategy is probably not appropriate for infected tibial IM nails;
          - drainage hole in the distal medial aspect of the femur may be created to allow thorough irrigation and drainage of the canal;
          - after fracture union, IM nail may then be removed & any residual infection is adressed;
                  - chronic osteomyelitis is rare;
    - aggressive infection:
          - more extensive infection may require external fixation;


- Examples:
    - 35 yo male who developed extensive chronic osteomyelitis following IM nail insertion;
         













Original Text by Clifford R. Wheeless, III, MD.