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Grade IIIB Open Tibial Frx


- See: Tibia Fracture Menu and Gustilo Classification:

- Discussion:
    - is frx in which there has been extensive stripping of soft tissues and periosteum from bone & where devitalization or loss of soft tissues
         usually requires plastic reconstructive procedures for closure;
         - extensive soft tissue loss with periosteal stripping and sig. wound contamination;
    - segmental defects measuring, on average, 10 cm were managed by:

- Initial Treatment and Timing of Surgery:
    - preoperative antibiotics;
           - therapeutic doses of ancef and tobramycin for 48 hrs are appropriate;
                  - despite the added cost, tobramycin is more effective against pseudomons and has a lower incidence prevalence of nephrotoxicity;
                  - note that the most frequently identified organisms in open tibial fractures are Staph aureus and nocosomial organisms;
           - tetanus prophylaxis if appropriate;
    - references:
           - Outcomes in open tibia fractures: relationship between delay in treatment and infection.
           - Efficacy of primary wound cultures in long bone open extremity fractures: are they of any value?
           - Efficacy of cultures in the management of open fractures.


- Soft Tissue Defects:
    - initial wound care:
    - pressure irrigation:
    - debridement and wound closure:
          - consider debriding the wound with a separate set of surgical instruments / drapes
          - in most cases, the surgeon will close surgical incisions made during the case but to leave the traumatic wound open;
                 - leaving the wound open maximizes drainage and wound tension (which is frequently present w/ primary closure);
                 - at 2nd look debridement (at 48-36 hrs), the edema will have diminished and the  wound can be closed w/ less tension;
          - references:
                 - Primary or delayed closure for open tibial fractures.
                 - Timing of closure of open fractures.
    - wound dressings: (see wound VAC);
           -ref: The use of a subatmospheric pressure dressing to salvage a Gustilo grade IIIB open tibial fracture with concomitant osteomyelitis to avert a free flap.
    - antibiotic bead pouch:
          - as noted by Keating et al 1996, bead pouches help reduce the infection rate in open tibia frx from 16% to 4%;
          - add 2.4 gm of tobramycin per cement package, and fashion small beads attached to a O silk suture;
          - counting the beads and adding methylene blue helps ensure that none of the beads will be left behind at removal;
          - a small drain is left adjacent to the beads and the wound is sealed w/ Opsite;
          - references:
                 - Reamed Nailing of Open Tibial Fractures: Does the Antibiotic Bead Pouch Reduce the Deep Infection Rate?
                        JF Keating et al.  J. Orthop. Trauma. 1996. Vol 10, No 5. p 298-303.
    - soft tissue coverage for tibial defects
          - note that if a external fixator is being considered, it should be placed in a way so as not to interfere w/ flap
                 application (eg a medially placed external fixator might interfere w/ a medial gastrocnemius flap);
          - references:
                 - The Timing of Flap Coverage, Bone-Grafting, and Intramedullary Nailing in Patients Who Have a Fracture of the Tibial Shaft With Extensive Soft-Tissue Injury.
                           MD Fischer et al.  JBJS 73-A. 1991. p 1316-1322.
                 - Early microsurgical reconstruction of complex trauma of the extremities.
                 - Primary versus delayed soft tissue coverage for severe open tibial fractures. A comparison of results.
                 - The use of a subatmospheric pressure dressing to salvage a Gustilo grade IIIB open tibial fracture with concomitant osteomyelitis to avert a free flap.


- Fracture Management:
    - external fixation:
           - some prefer the external fixator, adding limited internal fixation when required to improve joint surface congruity;
           - w/ an open frx, external fixation should include the foot to prevent soft tissue motion over the fracture;
           - exchange IM nailing may be preferable once soft tissue reconstructive surgery has been performed; 
           - in the study by Webb et al - JBJS 2007, the authors determined that:
                   - patients treated with an ex fix  had more surgical procedures, took longer to achieve full wt-bearing status, and had more infections and
                            nonunions (compared to IM nailing group);
                   - worst functional results were found in patients treated with ex fix and muscle flap (had worst outcomes than BKA)
           - references:
                   - Open grade III “floating ankle” injuries: a report of eight cases with review of literature
                   -
Analysis of Surgeon-Controlled Variables in the Treatment of Limb-Threatening Type-III Open Tibial Diaphyseal Fractures  
    - intramedullary nailing
           - references:
                  - Reamed nailing of Gustilo grade-IIIB tibial fractures.
                  - Open tibial fractures: faster union after unreamed nailing than external fixation.
                  - Emergency management of type IIIB open tibial fractures.
                  - Clinical results of primary intramedullary osteosynthesis with the unreamed AO/ASIF tibial intramedullary nail of open tibial shaft fractures.
                  - Local or free muscle flaps and unreamed interlocked nails for open tibial fractures.
                  - Treatment of type II, IIIA, and IIIB open fractures of the tibial shaft: a prospective comparison of unreamed interlocking IM nails and half-pin external fixators.
                  - Nonreamed locking intramedullary nailing for open fractures of the tibia.
                  - Reamed interlocking intramedullary nailing of open fractures of the tibia.
                  - Locking intramedullary nailing with and without reaming for open fractures of the tibial shaft. A prospective, randomized study.
                  - Contaminated fractures of the tibia: a comparison of treatment modalities in an animal model.
                  - The treatment of open tibial shaft fractures using an interlocked intramedullary nail without reaming.
    - soft tissue management:
           - filling of osseous defect w/ ATB-impregnated polymethylmethacrylate beads & coverage of soft-tissue defect by local myoplasty or free muscle transfer;
           - by definition soft tissue coverage is usually required;
    - bone grafting:
           - elevation of the flap after about four to six weeks and packing of the osseous defect with large amounts of autogenous
                  cancellous bone graft from the iliac crest;



Open type IIIB and IIIC fractures treated by an orthopaedic microsurgical team.

Reconstruction of large diaphyseal defects, without free fibular transfer, in Grade-IIIB tibial fractures.

Classification of type III (severe) open fractures relative to treatment and results.

Severe open fractures of the tibia

Severe open tibial fractures: a study protocol.

Treatment of grade IIIB open tibial fractures.  P. Tornetta et al.  JBJS.  Vol 76-B. p 13-19. 1994.

The use of a subatmospheric pressure dressing to salvage a Gustilo grade IIIB open tibial fracture with concomitant osteomyelitis to avert a free flap.

Analysis of Surgeon-Controlled Variables in the Treatment of Limb-Threatening Type-III Open Tibial Diaphyseal Fractures.










Original Text by Clifford R. Wheeless, III, MD.

Last updated by Clifford R. Wheeless, III, MD on Sunday, December 16, 2007 6:15 pm