Tracking Pixel
presents
Wheeless' Textbook of Orthopaedics

Disc Herniation



- See:
        - Herniated Disc in the Child:
        - Intervertebral Discs:

- Anatomy:
    - disc herniation may vary in severity from disc protrussion to disc extrusion, to finally disc sequestration;
    - disc containment:
          - w/ a contained disc herniation, the disc material herniated through the inner annulus but not the outer annulus;
                  - the material is therefore contained, but still can distort the path of the nerve;
          - w/ a non contained herniation, the disc material penetrates both the inner and out layers of the annulus;
                  - the material may reside beneath the posterior longitudinal ligament or may penetrate through it, or can
                          be sequestered as a free fragment;
    - posterolateral disc herniation:
          - protrusion is usually posterolateral into vertebral canal, where it may compress the roots of a spinal nerve;
          - in the case of a posterolateral herniation, the disc will not affect nerve corresponding in number to that
                  intervertebral discs (that nerve emerges above the disc);
                  - note that each nerve emerges thru upper part of foramen and lies against body of vertebra above;
          - protruded disc usually compresses next lower nerve as that nerve crosses level of disc in its path to its foramen;
                  - hence, protrusion of fifth lumbar disc usually affects S1 instead of L5;
          - in this case, an L4-L5 disc herniation will protrude on the L5 nerve root;
    - central (posterior) herniation:
          - in the lower lumbar segments, central herniation may result in S1 radiculopathy
          - less frequently, a protruded disc above second lumbar vertebra may compress spinal cord itself or
                  or may result in cauda equina syndrome;
    - far lateral disc herniation:
          - may compress the nerve root above the level of the herniation (hence a L4-L5 far lateral herniation may result in a L4 radiculopathy);
          - occurs in 6-10% of all lumbar disc herniations;
          - L4 nerve root is most often involved;
          - patient typically have intense radicular pain (sciatic 25% and femoral 75% of the time);
                  - when pain is femoral, sleep in the prone position is especially painful;
          - localized steroid injection:
                  - in the study by Weiner and Fraser (JBJS 1997), sustained relief of symptoms occured in 27 out of 30 patients;
          - surgical approach may consist of a muscle splitting intertransverse approach, which gives an excellent exposure of
                  to the spinal nerve and dorsal root ganglion;
    - references:
          - Foraminal and extraforaminal lumbar disk herniations.
          - Far lateral lumbar disc herniation.   The key to the intertransverse approach.
                  LJ O'hara and RW Marshall.   JBJS. Vol 79-B. No 6. Nov 1997. p 943.
          - The paraspinal sacrospinatus splitting approach to the lumbar spine.
                  LL Wiltse.   CORR. Vol 91. 1973. p 48-57.
          - Foraminal injection for lateral lumbar disc herniation.
                  BK Weiner and RD Fraser.   JBJS. Vol 79-B. No 5. Sep 1997. p 804.


- Disc Pressure / Failure:
    - intradiscal pressure is higher when sitting than when standing;
    - sitting-leaning forward > sitting > standing > lying on side > supine;
    - rotation combined w/ flexion are the worst positions for disc injury;
    - it is elevated by bending forward, bending to side, lifting, coughing, sneezing, and straining;
    - flexion, extension, and lateral bending all produce small displacements of the nucleus;
          - asymmetric & cyclic loading combined w/ lateral bend, compression, and flexion are risk factors for disk herniation;



- Clinical Presentation and Diff Dx:
    - discogenic pain:
    - w/ radiculopathy, there should be a predominance of leg pain over back pain;


- Exam: (neurological exam and exam of the lumbar spine)
    - straight leg raise: used to diagnose L5 and S1 radiculopathy;
    - femoral stretch test: used to diagnose L4 radiculopathy;
          - this test is performed by raising the leg while the patient is prone;
    - wt relief flexion test:


- MRI of Disc Herniation:


- Natural History:
    - prognosis of disc herniation is generally good regardless of treatment;
    - patients operated on for proven disc herniations improved more rapidly
            than patients treated non operatively;
    - within 4-5 years both operative and non operative treatment groups will
            generally have comprable neurologic recovery;
            - hence long term results are similar w/ or w/o surgery;
    - of all patients who sustain acute sciatica, less than 25% will require surgery;
    - despite the generally good prognosis, some patients will not recover such as
            this patient who had chronic anterior compartment atrophy and a mild foot
            drop (he was never treated operatively);


- Invasive Managment:
    - epidural steroid injection:
            - best effects are found in patients whose leg pain (or radicular symptoms) are worse than back pain;
            - at least one epidural injection should probably be tried in most patients with a disc herniation since
                    it is often the inflammation generated from the disc which causes symptoms rather than direct
                    mechanical compression from disc material;
    - selective nerve root injection:
            - contrast radiculogram is made to ensure that the correct nerve root was being injected;
            - patient was placed prone on a fluoro table;
            - C arm is adjusted to allow visualization of the target area in posteroanterior, oblique, and lateral positions;
            - entry site should allow visualization of the lateral edge of the pars interarticularis, transverse process, and articular facets
                    on the side to be injected was selected within a few centimeters lateral to the spine;
                    - disc space at that level is typically profiled;
            - use 22-gauge spinal needle with a short bevel and consider bending the tip for easier entry;
            - injection is delivered into the anterosuperior portion of the selected lumbar foramen;
            - contrast solution is injected under fluoroscopic control inorder to verify proper needle placement and to
                    verify absence of intravascular injection;
            - inject one cc of 0.25 % bupivacaine along with one cc of betamethasone (six milligrams per cc);
            - outcomes:
                    - in the report by KD Riew MD et al., the authors performed a prospective study on the effect of nerve-root
                          injections on the need for operative treatment of lumbar radicular pain;
                          - 29 of the 55 patients, all of whom had initially requested operative treatment, decided
                                  not to have the operation during the follow-up period (range, thirteen to 28 months)
                                  after the nerve-root injections;
                          - of the 27 patients who had received bupivacaine alone, nine elected not to have the operation;
                          - of the 28 patients who had received bupivacaine and betamethasone, 20 decided not to have the operation;
                          - difference in the operative rates between the two groups was highly significant (p < 0.004);
                          - the authors concluded that selective nerve-root injections of corticosteroids are significantly more effective
                                  than those of bupivacaine alone in obviating the need for a decompression for up to 13 to 28 months
                                  following the injections in operative candidates;

    - references:
            - The use of epidural steroids in the treatment of lumbar radicular pain. A prospective, randomized, double-blind study.
            - The Effect of Nerve-Root Injections on the Need for Operative Treatment of Lumbar Radicular Pain. A Prospective, Randomized, Controlled, Double-Blind Study*
                  KD Riew MD et al. J Bone Joint Surg Am 82-A: 1589-93, 2000
    - percutaneous discectomy
    - diskectomy
    - post operative management:


- Complications:
    - Post Operative Diskitis:




Lumbar disc excision in children and adolescents.

The form and structure of the extruded disc.

Biochemical changes associated with the symptomatic human intervertebral disk.

Lumbar disc herniation: Controlled prospective study with 10 years of observation.
      Webber H: Spine 1983;8:131-140.

Histological changes in aging lumbar intervertebral discs. Their role in protrusions and prolapses.

Histological development of intervertebral disc herniation.

Lower-extremity sensibility testing in patients with herniated lumbar intervertebral discs.

Back pain and sciatic.  
    JW Frymoyer.   N. Engl. J. Med. Vol 318. 1988. p 291-300.

Surgery for lumbar disc herniation: What are the choices?
    DB Murrey MD and EN Hanley MD.   The journal of musculoskeletal medicine. Jan. 1999. p 39.















Original Text by Clifford R. Wheeless, III, MD.